With the game seemingly heading for a 1-1 draw, the Brazilian forward delivered a moment of real quality in the 90th minute, heading home with a powerful home run to beat Sailani 2-1 from a corner.
Although still at the start of the season, the result can be crucial in the title race, with both sides advancing to the top spot before the kickoff.
The victory now gives the reigning champion three points from his opponents as he marks the rest of the league.
Speaking after the match, Liverpool boss Jugan Klopp said his side deserved the late winner and praised Fermino for his third league goal of the season.
“It was a really good game from us. It’s the way you have to play. You have the potential, you score goals,” Klopp told BBC Radio 5 Live. .
“I like talking to Bobby [Firmino] Goals but it always seems like we’re surprised […] It’s not so low that he scored.
“He’s a top notch player and he scores but he needs to do something for us that sometimes keeps him out of the box for us. I can’t be happier for him and for us because it’s a Was the top goal and very important. “
‘Best team lost’
Liverpool are now unbeaten in their last 66 league games at Anfield, but could easily have lost the record on Wednesday.
As expected, Jose Mourinho defended his opponent Liverpool and his game plan was almost paid off.
Steven Bergwijn hit the post and Harry Kane dramatically missed in the second half from close range in a few minutes, but the visitor was left to make up for missed chances.
After the match, Mourinho told Amazon Prime, “Not so close to winning, not so close to the draw,” so frustrated Mourinho told Amazon Prime.
“We missed chances, we had chances, we got the game under control. The draw will have a bad outcome so you can imagine how we feel about the defeat.
“Great performance, of course some mistakes, some things to improve, a very unfair result.
“Today, Liverpool was not like a team that is a champion, a European champion, a world champion. The difference was not on the pitch.”
As the referee blew the whistle full-time, the cameras showed Mourinho and Klopp involved in a touchline exchange that ended strangely by chance.
When asked what was shared, Mourinho said he had told Klopp that “the best team lost” and questioned the German animated antics on the touchline.
“They [Klopp] Disagree, but that’s his opinion, “Mourinho added.
The 73-year-old was credited with transforming the club during his successful reign with a resounding victory in the 2000-01 season.
Liverpool will now face a tough test outside Crystal Palace in the Premier League while sports hosts Leicester City.